To update the license key, launch the application as an administrator (Start Menu > All Programs > Aspera > Enterprise Server > Enterprise Server) and click Tools > License to open the License window.
You can either click the Import License File and select the license file, or click Paste License Text to paste the copied content of the license file. When finished, the license information will appear in the window. Verify that it is correct and click Close.
If you are using the Node API, reload the asperanoded service.
> asnodeadmin.exe --reload